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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 8
  • Receptor, Epidermal Growth Factor - »õâ A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
    Synonyms : Epidermal Growth Factor Receptor Kinase, Receptors, Epidermal Growth Factor, Epidermal Growth Factor Receptor Protein Tyrosine Kinase, Proto-Oncogene Protein, erbB-1, Receptor, TGF alpha, Receptor, Transforming Growth Factor alpha, c erbB 1 Protein
  • Receptor, erbB-2 - »õâ A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.
    Synonyms : Oncogene Protein HER-2, Proto-Oncogene Proteins c-erbB-2, Receptors, erbB-2, p185(c-neu), HER 2 Proto Oncogene Protein, Oncogene Protein HER 2, Proto Oncogene Protein HER 2, Proto Oncogene Proteins c erbB 2, Proto-Oncogene Protein, HER-2, Receptor, erbB 2
  • Receptor, erbB-3 - »õâ A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis.
    Synonyms : Proto-Oncogene Protein c-erbB-3, Proto-Oncogene Proteins erbB-3, HER 3 Proto Oncogene Protein, Proto Oncogene Protein c erbB 3, Proto Oncogene Protein erbB 3, Proto Oncogene Proteins erbB 3, Proto-Oncogene Protein, HER-3, Receptor, erbB 3, c erbB 3 Protein
  • Receptor, Fibroblast Growth Factor, Type 1 - »õâ A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.
    Synonyms : FGFR1 Protein, FGFR1 Tyrosine Kinase, Fibroblast Growth Factor Soluble Receptor 1, fms-Like Tyrosine Kinase-2, fms Like Tyrosine Kinase 2
  • Receptor, Fibroblast Growth Factor, Type 2 - »õâ A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in APERT SYNDROME.
    Synonyms : BEK Fibroblast Growth Factor Receptor, BEK Fibroblast Growth Factor Receptor Kinase, BEK Protein Tyrosine Kinase, Bek Fgf Receptor Kinase, Bek-Related Fibroblast Growth Factor-Receptor-1, FGFR2 Protein, FGFR2b, FGFR2c, Fibroblast Growth Factor Receptor 2b
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 8
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